Which of the following is the correct order of the class I processing pathway?
A. peptides exported from the ER by TAP > peptides are digested by the proteasome > peptides are loaded onto class I > class I is exported to the cell surface
B. proteins are digested by the proteasome > peptides are imported into the ER by TAP > peptides are loaded onto MHC class I > class I is exported to the cell surface
C. MHC class I moves from the cell surface to the lysosome by endocytosis > class I bound peptides are replaced with antigenic peptides in the lysosome > class I returns to the cell surface
D. proteins are degraded by TAP > peptides are imported into the lysosome by the proteasome > peptide-MHC class I complexes are exported to the cell surface
Select your answer:
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