Medical Quiz

Lipid Metabolism Quiz

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What is the primary site for ketogenesis?

A. Liver mitochondria

B. Adipose tissue

C. Muscle cells

D. Pancreas


What is the primary site for ketogenesis?

A. Liver mitochondria

B. Adipose tissue

C. Muscle cells

D. Pancreas


Which of the following is NOT a health risk associated with excess fat located in the central abdominal area?

A. Hypertension

B. Insulin resistance

C. Diabetes

D. Arthritis


What is the major enzyme involved in the hydrolysis of triacylglycerols in the small intestine?

A. Gastric lipase

B. Pancreatic lipases

C. Hormone-sensitive lipase

D. Lipoprotein lipase


What is the purpose of the shuttle mechanism in fatty acid transport into the mitochondrial matrix?

A. To convert fatty acids into acetyl CoA

B. To convert acyl CoA into acetyl CoA

C. To convert acetyl CoA into acyl CoA

D. To convert acyl CoA into ketone bodies


What is lipolysis?

A. Hydrolysis of triacylglycerol

B. Formation of lipids

C. Breakdown of ketone bodies

D. Formation of ketone bodies


Which ketone body is produced first in the process of ketogenesis?

A. Acetoacetate

B. β-hydroxybutyrate

C. Acetone

D. Oxaloacetate


Identify the correct sequential enzymatic step for fatty acid synthesis:

A. Delta-2-enoyl CoA Dehydrate, Acyl CoA Dehydrogenase, Hydroxy acyl dehydrogenase, Thiolase

B. Hydroxy acyl dehydrogenase, Acyl CoA Dehydrogenase, Delta-2-enoyl CoA Dehydrate, Thiolase

C. Thiolase, Acyl CoA Dehydrogenase, Delta-2-enoyl CoA Dehydrate, Hydroxy acyl dehydrogenase

D. Acyl CoA Dehydrogenase, delta-2-enoyl CoA Dehydrate, Hydroxy acyl dehydrogenase, Thiolase


The acetyl CoA is produced in the mitochondria and must be transported into the cytosol for the synthesis of fatty acids. Which of the following is true regarding the transport of Acetyl CoA?

A. Acetyl CoA is diffused from the mitochondrial membrane

B. Acetyl CoA is transported by its specific transporter protein

C. Acetyl CoA is converted into pyruvate, enters into the cytosol and acetyl CoA is regenerated

D. Acetyl CoA is converted into citrate, enters into the cytosol and acetyl CoA is regenerated.


Name the energy source of the brain during starvation.

A. Fat

B. Ketone bodies

C. Protein

D. Lipids


What is the purpose of the shuttle mechanism in fatty acid transport into the mitochondrial matrix?

A. To convert fatty acids into acetyl CoA

B. To convert acyl CoA into acetyl CoA

C. To convert acetyl CoA into acyl CoA

D. To convert acyl CoA into ketone bodies


What are ketone bodies usually synthesized from?

A. Acetyl-CoA

B. Pre-B cell

C. Methionine

D. Pyruvate


Which of the following is the rate-limiting step of fatty acid oxidation and is also inhibited by malonyl CoA?

A. Thiokinase

B. Carnitine Palmitoyl transferase I

C. Acyl CoA Dehydrogenase

D. Thiolase


Which ketone body is produced first in the process of ketogenesis?

A. Acetoacetate

B. β-hydroxybutyrate

C. Acetone

D. Oxaloacetate


Which of the following is NOT a ketone body?

A. Acetoacetate

B. β-hydroxybutyrate

C. Acetone

D. Glycerol


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