Medical Quiz

ESR (RBC sed rate) Quiz


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polycythemia vera, the RBC count is increased; the blood is more viscous

A. fall faster,
increasing ESR

B. fall slower,
decreasing ESR


test is specific for a specific disease. i.e. Rheumatoid Arthritis

A. Acute Phase Reactants

B. Erythrocyte Sedimentation Rate

C. C-Reactive Protein

D. none


ESR
Settling dependent on ______

A. protein composition of plasma (fibrinogen)

B. size and shape of erythrocytes

C. erythrocyte concentration

D. all of the above


decrease of the zeta potential

A. fall faster,
increasing ESR

B. fall slower,
decreasing ESR


Specimens needs EDTA collection

A. Wintrobe or Modified Westergren

B. true Westergren


When inflammatory process is present, fibrinogen enters the blood in high amounts and causes red cells to stick to each other

A. CRP
C-Reactive Protein Test

B. ESR
Erythrocyte Sedimentation Rate


plays a part in your immune response by interacting with your body’s complement system

A. CRP
C-Reactive Protein Test

B. ESR
Erythrocyte Sedimentation Rate


will remain elevated for several days until excess fibrinogen is removed from the serum

A. CRP
C-Reactive Protein Test

B. ESR
Erythrocyte Sedimentation Rate


Males, 0-15 mm/hr; >50 yrs. old 0-20 mm/hr
Females, 0-20 mm/hr; >50 yrs. old 0-30 mm/hr

A. Westergren method

B. Modified Westergren method

C. Alifax Roller 20-Sysmex

D. all of the above


Serum glycoproteins

Levels increase quickly in response to injury or trauma to tissues and during infections

They are non-specific indicators of inflammation (i.e., cannot diagnose a specific infectious agent or process)

A. Acute Phase Reactants

B. Erythrocyte Sedimentation Rate

C. C-Reactive Protein

D. none


first 24 hours of a disease process, the ____ may be normal and ____ elevated

A. ESR
CPR

B. CPR
ESR

C. Acute Phase Reactants,
CPR

D. ESR,
Acute Phase Reactants


first 10 minutes, initial period of aggregation, rouleaux is formed

A. Lag phase

B. Decantation phase

C. Packing phase


1.Tilting the tube
2. Increasing the length of the tube
3. Temperature above room temp

A. fall faster,
increasing ESR

B. fall slower,
decreasing ESR


decreased numbers of RBC’s (anemia)

A. fall faster,
increasing ESR

B. fall slower,
decreasing ESR


Specimens needs Sodium Citrate tube collection

A. Wintrobe or Modified Westergren

B. true Westergren


Cells with abnormal shapes (poikilocytes such as sickle cells or spherocytes)

A. fall faster,
increasing ESR

B. fall slower,
decreasing ESR


1. Decreased diameter of the tube
2. Using old blood collected longer than 2 hrs
3. Temperature decrease below 20ºC
4. incorrect anticoagulant to blood ratio
5. air bubbles
6.Partially clotted samples (uses up fibrinogen).

A. fall faster,
increasing ESR

B. fall slower,
decreasing ESR


allowed to sediment at an angle of 18º and read at the appropriate time, the total analysis time is 20 minutes

A. Westergren method

B. Modified Westergren method

C. Alifax Roller 20-Sysmex

D. all of the above


Increasing levels of plasma proteins (primarily fibrinogen, alpha globulins, or gamma globulins)

A. fall faster,
increasing ESR

B. fall slower,
decreasing ESR


final period, RBCs crowd closely together, last 10 minutes

A. Lag phase

B. Decantation phase

C. Packing phase


Automated ESR Methods
Roller Principle

A. measures RBC aggregation and extrapolates the sedimentation rate

B. degree of settling of RBCs in plasma in an anticoagulated specimen during a specific time


usually performed in Chemistry or Immunology Dept of Laboratory

A. CRP
C-Reactive Protein Test

B. ESR
Erythrocyte Sedimentation Rate


usually changes more rapidly, because it is made by the liver and secreted hours after the beginning of infection or inflammation

A. CRP
C-Reactive Protein Test

B. ESR
Erythrocyte Sedimentation Rate


Sodium citrated whole blood (blue topped tube).   The diluted blood is aspirated into a calibrated ESR column and the cells are allowed to settle for a period of exactly one hour. 

A. Westergren method

B. Modified Westergren method

C. Alifax Roller 20-Sysmex

D. all of the above


period of fast settling, usually lasts about 40 minutes

A. Lag phase

B. Decantation phase

C. Packing phase




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