Immunology Quiz
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A small injected dose of a pathogen that stimulates the production of antibodies is:
A. histamine
B. interferon
C. pathogen
D. vaccine
In Rocket Electrophoresis, a higher antigen concentration is proportional to:
A. The time of incubation until the reaction is finished
B. The size of the agglomerate
C. The length of the precipitin arc or rocket.
D. The length of the arc formation when two antigens are identical
What is the name of the area marked A?
A. Variable region
B. Constant region
C. Light chain
D. Heavy chain
Which of the following complement components has chemotactic activity?
A. C3b
B. C3a
C. C1qrs
D. C5b6789
It is an agglutination reaction where the positive result is the lack of agglutination.
A. Reverse Passive Agglutination
B. Coagglutination
C. Agglutination Inhibition
D. Indirect Agglutination
In the precipitin curve, the zone where there is maximum antibody bound to the least amount of antigen is known as:
A. Ozone
B. Prezone
C. Postzone
D. Zone of Equivalence
Which of the following is NOT a symptom of tuberculosis?
A. Coughing
B. Fever
C. Shortness of breath
D. Short-term memory loss
MHC molecules containing beta-2 microglobulin:
A. contain alpha and beta transmembrane polypeptides
B. participate in the activation of CD4+ T cells
C. are determined by MHC-A, MHC-B and MHC-C genes
D. are determined by MHC-DR genes
E. all of the above
Patients undergoing treatment with complement therapeutics for hereditary angioedema (HAE) would expect to have which of the following laboratory values?
A. normal C4 and C2
B. decreased C4 and C2
C. increased C4 and C2
D. increased C4 and low C2
A new assay is used to test 120 samples from patients with a clinically confirmed diagnosis of the relevant infection and 50 samples from healthy control subjects. The test results were positive for 90 of the infected patients and positive for 10 of the healthy controls.
Calculate the assay’s specificity.
A. 57%
B. 75%
C. 80%
D. 90%
Which of the following can be donated by a live donor?
A. Kidney
B. Heart
C. Eye
D. Lung
The information needed to make all proteins, including antigen receptors, is in the genome.
A. TRUE
B. FALSE
Endogenous peptides binding to MHC-A, MHC-B or MHC-C molecules on the surface of hepatocytes are critical for the response by:
A. B cells
B. helper T cells
C. cytotoxic T cells
D. macrophages
What are the names of the structures
A. vector/interferon
B. pathogen/mucus
C. antibody/antigen
D. penicillin/histamine
Which cell type would be most likely NOT to express detectable MHC I?
A. dendritic cells
B. macrophages
C. erythrocytes
D. intestinal epithelial cells
T cell interacts with APCs in ……………….. in …………………
A. Follicle, Spleen
B. PALS, Spleen
C. PALS, Lymph node
D. Follicle, Lymph node
MHC restriction refers to
A. T-cells ability to restrict MHC expression
B. T-cells only recognize MHC molecules that were present during development
C. T-cells may interact with both MHC-I or MHC-II
D. Dendritic cells may present antigen to any T-cell regardless of genetic background
On a TCR, gene recombination occurs
A. in variable region only
B. in variable region and joining region
C. in variable, joining, and constant regions
D. in constant region only
What results in gene diversity?
A. Gene recombination
B. Somatic mutation
C. Gene conversion
D. All the above
In the Ouchterlony method, this formation of the precipitin line indicates that the antigens are partially identical.
A. An Arc Formation
B. A spur formation
C. A cross formation
D. Lattice Formation
The active stage of a virus’s life cycle is called the…
A. Lysogenic phase
B. Luteal phase
C. Lytic phase
D. Lying phase
MHCI is expressed on
A. Only antigen presentation cells
B. All nucleated cells
C. Only macrophages
D. Only NK cells
A. Epilepsy
B. Meningitis
C. Bone joint inflammation
D. Pot’s spine
A small child suffers from repeated viral infections and has trouble clearing virally infected cells. Which arm of adaptive immunity is likely defective?
A. Complement
B. Cell-mediated immunity
C. Humoral immunity
D. NK-cells
C5b6789 functions in:
A. target cell lysis
B. recongnition of antigen
C. chemotaxis
D. complement inhibition
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