Immunology: T cell Development Quiz
Preview:
Which of the following statements about the thymus is true?
A. the thymus is fully developed after the age of 1
B. the thymus if fully developed before birth
When the beta chain is produced, is forms a complex with ___
A. CD4
B. CD3
Where do T cells develop?
A. bone marrow
B. thymus
Notch 1- means the progenitor becomes a
A. T cell
B. B cell
Progenitor cells are not committed to the T lineage when they enter the thymus.
A. TRUE
B. FALSE
Thymocytes that lack the TCR but beginning to rearrange their TCR genes
A. double negative thymocytes
B. double positive
Which of the following about the thymus is true?
A. the thymus begins to degenerate at the age of 25
B. the thymus begins to degenerate at the age of 1
Which rearrangement is first during the double negative stage?
A. beta chain
B. alpha chain
Which of the two lineages make the majority of T cells?
A. aB
B. yG
Immature T cells
A. thymocytes
B. progenitor cells
Which receptor signaling commits the progenitor cell to the T lineage?
A. Notch 1
B. not this
T lymphocytes derive from the common myeloid progenitor
A. TRUE
B. FALSE
Notch +1 means the progenitor becomes a
A. T cell
B. B cell
T cells are involved in the ___ immune response.
A. innate
B. adaptive
The thymus and the proportion of T cells it produces increases with age.
A. TRUE
B. FALSE