Hematology & Blood Banking Quiz
Preview:
Multiple myeloma is a tumour of plasma cells that accumulate in the bone marrow,
A. Stem cells
B. B lymphocytes
C. Plasma cells
D. Hemopoietic stem cells
Philadelphia (Ph) chromosome is the definitive diagnosis of:
A. CML
B. AML
C. CLL
D. ALL
JACK2 mutation is most commonly characteristic feature of which type of disease?
A. Polycythemia vera
B. Primary myelofibrosis
C. Essential thrombocythemia
D. Non-Hodgkin lymphoma
Burkitt’s cells are found in:
A. ALL-L2
B. ALL-L3
C. AML-M1
D. AML- M7
The major subdivision of lymphomas is into Hodgkin lymphoma and non‐Hodgkin lymphoma and this is based on:
A. Presence of Lacunar Cells
B. Presence of Popcorn Cells
C. Presence of Mummified cells
D. Presence of Reed Sternberg cells
The Staging of Hodgkin lymphoma are done by clinical representation along with:
A. CBC, Bone marrow finding, Immunophenotyping
B. Chromosomal analysis, Karyotyping and gene mutation
C. Radiological Scan like X-ray, CT & MRI
D. Only on X-ray
Myelodysplasia includes a group of clonal disorders of _______ that lead to bone marrow failure and low blood cell counts.
A. Hepatocyte abnormality
B. Nervous tissue abnormality
C. Reticoendothelial tissue / cells
D. Hematopoitic stem cells
A patient is found to have elevated kappa and lambda serum‐free light chains, but the kappa/lambda ratio is raised from the normal range. Which ONE of the following is the most likely cause of this laboratory finding?
A. Non-Hodgkin Lymphoma
B. Burkit’s lymphoma
C. Lacunar myeloma
D. Multiple myeloma
A patient’s complete blood count shows MCV is lower than 80fl & MCH is lower than 27pg & peripheral smear show abnormal erythroblasts containing numerous iron granules arranged in a ring or collar around the nucleus. What provisional diagnosis can be made by a Hematologist?
A. Sidero-blastic anemia
B. Thalassemia
C. Anemia of chronic disease
D. Hemolytic anemia
Genetic defect of red cells destruction in hemolytic anemia are:
A. Myeloproliferative disorder, CLL, AML
B. Red cell membrane defect, Enzyme Deficiency, Hb defect
C. Spleen disorder, liver abnormality, bone marrow disorder
D. Erythropoietin deficiency, vitamin B12 and free iron deficiency