Baclofen acts on GABA receptors. Which of the following is TRUE regarding GABA receptors?
A. GABA receptors are ionotropic. Upon activation the ion channel opens and chloride can enter the cell causing it to hyperpolarize.
B. In addition to GABA binding sites, GABA receptors have additional benzodiazepine binding sites.
C. Activation of GABA receptors generate excitatory postsynaptic potentials (EPSPs).
D. GABA receptors are metabotropic receptors. Activation of the G-protein coupled receptor leads to second messenger activation by the alpha subunit and activation of potassium channels by the beta/gamma subunits.
Select your answer:
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