Medical Quiz

Hematology Acute Leukemias Quiz


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A gap in the normal maturation of cells with many blasts and few mature forms is known as:

A. leukemia hiatus

B. chronic leukemia

C. mixed cell lineage

D. Leukoerythroblastic reaction


The stain helpful in distinguishing myeloblasts from lymphoblasts is:

A. Myeloperoxidase

B. TRAP

C. LAP

D. esterase


A patient with a hypercellular, dysplastic BM; anemia; and neutropenia in peripheral blood most likely has which of the following neoplasms?

A. MPN

B. MDS

C. AML

D. ALL


A leukemia that shows a profusion of granulocytes at all stages of development from blasts to segmented neutrophils is:

A. AML

B. CML

C. ALL

D. CLL


Auer rods may be seen in which of the following cells?

A. Myeloblasts

B. Myelocytes

C. Lymphoblasts

D. Megakaryoblasts


Which cytochemical reaction is most helpful in identifying the blasts in acute monoblastic leukemia?

A. NSE

B. TdT

C. PAS

D. SBB


What is the required blast percentage for the diagnosis of acute myeloid leukemia recommended by WHO?

A. 10%

B. 20%

C. 30%

D. 40%


An elderly patient with a WBC of >100,000 and 95% small mature lymphocytes on the peripheral smear is most likely associated with:

A. PLL

B. ALL

C. CLL

D. CML



The cell on the left would most likely be seen in:

A. Infectious lymphocytosis

B. Toxoplasmosis

C. Bordetella pertussis infection

D. Acute monoctyic leukemia


The PAS stain is helpful in diagnosing:

A. CLL

B. CML

C. MDS

D. ALL



The cells at the arrows are called what and would be seen in which leukemia?

A. Smudge Cells
ALL

B. Monocytes
Acute monocytic leukemia

C. Smudge Cells
CLL

D. Pyknotic nuclei
none


CD2, CD3, and CD4 are present on the cells found in a patient with an undiagnosed leukemia. The most likely leukemia present is:

A. Pre-B cell ALL

B. Pro-B-cell ALL

C. T-cell ALL

D. ALL- Burkitt’s type


Myeloperoxidase stain is strongly positive in:

A. Acute lymphoblastic leukemia

B. Acute monocytic leukemia

C. Acute megakaryoblastic leukemia

D. Acute myeloblastic leukemia


The monoclonal marker that would be positive in a B cell lymphoblastic leukemia is:

A. CD1

B. CD7

C. CD19

D. CD33


Which of the following is most often associated with acute leukemia?

A. Erythrocytosis and Thrombocytosis

B. Neutropenia and thrombosis

C. Anemia and Thrombocytopenia

D. Lymphocytosis and thrombocytopenia




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