Medical Quiz

Molecular Basis of Inheritance Quiz


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The three codons which result in the termination of polypeptide chain synthesis are:

A. UAA, UAG, GUA

B. UAA, UAG, UGA

C. UAA, UGA, UUA

D. UGU,UAG, UGA


Which of the following phenomena was experimentally proved by Meselson and Stahl?

A. Transduction

B. Semi-conservative DNA replication

C. Transformation

D. Central dogma


Chemically, RNA is (i) reactive and (ii) stable as compared to DNA.

A. (i) equally, (ii) equally

B. (i) less, (ii) more

C. (i) more, (ii) less

D. (i) more, (ii) equally


The human chromosome with the highest and least number of genes in them are respectively:

A. chromosome 21 and Y

B. chromosome 1 and X

C. chromosome 1 and Y

D. chromosome X and Y.


The structure in chromatin seen as ‘beads-on string’ when viewed under an electron microscope are called:

A. nucleotides

B. nucleosides

C. histone octamer

D. nucleosomes.


To prove that DNA is the genetic material, which radioactive isotopes were used by Hershey and Chase (1952) in experiments?

A. 33S and 15N

B. 32P and 35S

C. 32P and 15N

D. 14N and 15N


First experimental proof for semi-conservative DNA replication was shown in:

A. Streptococcus pneumonia

B. Escherichia coli

C. Neurospora crassa

D. Rattus rattus.


The net electric charge on DNA and histones is:

A. both positive

B. both negative

C. negative and positive, respectively

D. zero.


In a DNA strand, the nucleotides are linked together by:

A. glycosidic bonds

B. phosphodiester bonds

C. peptide bonds

D. hydorgen bonds.


Find out the wrong statement about heterochromatin:

A. It is densely packed

B. It stains dark.

C. It is transcriptionally active.

D. It is late replicating.


Which of the following statements is the most appropriate for sickle cell anemia?

A. It cannot be treated with iron supplements.

B. It is a molecular disease.

C. It confers resistance to acquiring malaria.

D. All of the above.


The process of transformation is not affected by which of the following enzymes?

a) DNase
b) RNase
c) Peptidase
d) Lipase

A. A, B

B. A, B, C, D

C. B, C, D

D. A, B, C


The first genetic material could be:

A. protein

B. cabohydrates

C. DNA

D. RNA


Histone proteins are:

A. basic, negatively charged

B. basic, positively charged

C. acidic, positively charged

D. acidic, negatively charged


n some viruses, DNA is synthesized by using RNA as a template. Such a DNA is called:

A. A – DNA

B. B – DNA

C. cDNA

D. rDNA.




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