Immunology: T cell Development Quiz
Preview:
Progenitor cells are not committed to the T lineage when they enter the thymus.
A. TRUE
B. FALSE
Which of the two lineages make the majority of T cells?
A. aB
B. yG
If the TCR binds strongly to MHC class I or II molecules then ___
A. the T cell survives
B. the T cell dies
Where do T cells develop?
A. bone marrow
B. thymus
The thymus and the proportion of T cells it produces increases with age.
A. TRUE
B. FALSE
Where do T cells go through selection and education processes?
A. bone marrow
B. thymus
T lymphocytes derive from the common myeloid progenitor
A. TRUE
B. FALSE
The first gene rearrangement in the double negative stage is of the ___ chain
A. beta chain
B. alpha chain
Thymic cells that produce growth factors and ligands that contribute to T cell development.
A. progenitor cells
B. stromal cells
When the beta chain is produced, is forms a complex with ___
A. CD4
B. CD3
Thymocytes that lack the TCR but beginning to rearrange their TCR genes
A. double negative thymocytes
B. double positive
Notch 1- means the progenitor becomes a
A. T cell
B. B cell
Once the complete T cell receptor is formed then the cell expresses
A. CD4
B. CD8
C. CD4 and CD8
Early T cell precursor development occurs in the ___
A. bone marrow
B. thymus
Growth factor that is secreted by thymic stromal cells
A. IL 7
B. IL8