Medical Quiz

Molecular Genetics Quiz


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A small circular piece of DNA found in bacteria are called …

A. recombinants

B. vectors

C. plasmids

D. prokaryotes


A mutation leading to an early ‘stop’ codon is a …

A. frameshift mutation

B. silent mutation

C. missense mutation

D. nonsense mutation


Translation occurs in the:

A. office

B. cytoplasm

C. nucleus

D. cell membrane


The process of using an mRNA to make a protein is called

A. Replication

B. Transcription

C. Translation

D. Cell Division


Which of the following enzymes is NOT needed in replication?

A. DNA ligase

B. RNA primase

C. DNA polymerase III

D. RNA polymerase


STRUCTURE: Which 2 molecules form the sides of the DNA ladder?

A. deoxyribose and adenine

B. deoxyribose and a hydrogen bond

C. sugar and the nucleus

D. deoxyribose (sugar) and phosphate


Humans have 23 pairs of chromosomes, and chimps have 24 pairs of chromosomes. What is the most likely explanation for these differences in human and chimp genomes?

A. At some point in evolution, human and chimp ancestors reproduced with each other.

B. In the evolution of chimps, new adaptations resulted from additional chromosomal material.

C. The common ancestor of humans and chimps had 24 pairs of chromosomes. During human evolution, two human chromosomes fused end to end.

D. Errors in mitosis resulted in an additional pair of chromosomes in chimps.


HISTORY: Took the X-Ray crystallography photographs that revealed that DNA is a Double Helix

A. Rosalind Franklin

B. Linnus Pauling

C. Fredrick Griffeth

D. Martha Chase


HISTORY: Discovered Bacterial Transformation

A. Fredrick Griffeth

B. Erwin Chargaff

C. Rosalind Franklin

D. Martha Chase


How many amino acids could be coded using the sequence 5’AUGCCCGUA3′

A. 1

B. 2

C. 3

D. 4


ATTTGAGCC- Original
ATTGAGCC – Mutated
The example above is an example of a

A. Insertion- Frameshift

B. Deletion- Substitution

C. Deletion -Frameshift

D. All of the above


STRUCTURE: Nucleotides monomers are made up of a sugar, a phosphate, and a:

A. nitrogenous base

B. nucleic acid

C. cholesterol

D. fatty acid


HISTORY: Discovered that A and T bond together and C and G bond together…

A. Watson and Crick

B. Rosalind Franklin

C. Fredrick Griffeth

D. Erwin Chargaff


STRUCTURE: What Nitrogenous Base does RNA contain that DNA does not?

A. Thymine

B. Uracil

C. Adenine

D. Love


What amino acid is represented by the codon UUA?

A. Phenylalanine

B. Tyrosine

C. Leucine

D. Stop codon


Any change in the sequence of DNA is…

A. transgenic shift

B. Single Genotype

C. Monohybrid Trait

D. Mutation


The replication of DNA is…

A. conservative

B. dispersive

C. semi-conservative

D. random


This is

A. tRNA

B. mRNA

C. DNA

D. a ribosome


Since most amino acids are encoded for by more than one codon, the genetic code is said to be …

A. semi-conservative

B. a triplet code

C. universal

D. redundant


Liver cells differ from skin cells mainly because they…

A. have unique ribosomes.

B. use different genetic codes.

C. contain different genes.

D. express different genes.


A codon is to mRNA as an anti-codon is to …

A. DNA

B. an amino acid

C. rRNA

D. tRNA


For a repressible operon to be transcribed, which of the following conditions must occur?

A. A corepressor must be present.

B. RNA polymerase and the active repressor must be present.

C. RNA polymerase must bind to the promoter, and the repressor must be inactive.

D. RNA polymerase must not occupy the promoter, and the repressor must be inactive


Which sequence of DNA bases would pair with this partial strand

ATG TGA CAG
_
A. ATG TGA CAG

B. TAC ACT GTC

C. GTA AGT GAC

D. CAT TCA CTG


Meselsohn and Stahl’s experiment showed that…

A. DNA is the hereditary material

B. one gene leads to one protein

C. DNA replication is semiconservative

D. the nucleus contains DNA


Which of the following facts did Hershey and Chase make use of in trying to determine whether DNA or protein is the genetic material?

A. DNA contains sulfur, whereas protein does not.

B. DNA contains purines, whereas protein includes pyrimidines.

C. DNA contains phosphorus, whereas protein does not.

D. DNA contains nitrogen, whereas protein does not.




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