Molecular Genetics Quiz
Preview:
A DNA molecule made from 2 different sources is called …
A. recombinant DNA
B. nuclear DNA
C. modified DNA
D. mutant DNA
Which of the following information or processes does gene therapy require?
A. the ability to introduce the normal allele into the patient
B. the knowledge and availability of the defective gene but not the normal allele
C. the ability to express the introduced gene at any time in the tissue site within the patient
D. the ability to introduce a defective allele into a patient
What is Cas9 and what does it do?
A. a protein enzyme that cuts both strands of DNA at sites specified by an RNA guide
B. a DNA sequence that binds the Cas9 protein
C. an RNA molecule that binds to target DNA via complementary base pairing
D. a viral protein that disrupts bacterial membranes
Which of the following processes do normal proto-oncogenes typically exhibit?
A. They normally suppress tumor growth.
B. They enhance tumor growth.
C. They stimulate normal cell growth and division.
D. They are underexpressed in cancer cells.
The two strands in a DNA molecule are held together by …
A. hydrogen bonds
B. phosphodiester bonds
C. covalent bonds
D. ionic bonds
The synthesis of a new strand of DNA …
A. starts at an operator sequence.
B. involves DNA ligase.
C. is always in fragments.
D. occurs from the 5′ end to the 3′ end.
HISTORY: Performed an experiment with Bacteriophage viruses that proved DNA was the genetic material
A. Maurice Wilkens and Rosalind Franklin
B. James Watson and Francis Crick
C. Alfred Hershey and Martha Chase
D. Peanut butter and Jelly
HISTORY: Discovered that A and T bond together and C and G bond together…
A. Watson and Crick
B. Rosalind Franklin
C. Fredrick Griffeth
D. Erwin Chargaff
Adenine bonds with ______________.
A. Guanine
B. Thymine
C. Cytosine
D. Adenine
Which of the following is not a post-transcriptional modification of mRNA?
A. addition of poly-A tail
B. addition of 5′ cap
C. removal of introns
D. removal of exons
The replication of DNA is…
A. conservative
B. dispersive
C. semi-conservative
D. random
For a repressible operon to be transcribed, which of the following conditions must occur?
A. A corepressor must be present.
B. RNA polymerase and the active repressor must be present.
C. RNA polymerase must bind to the promoter, and the repressor must be inactive.
D. RNA polymerase must not occupy the promoter, and the repressor must be inactive
A type of substitution in which no amino acids change is called
A. Missense
B. Nonsense
C. Silent
D. Deletion
In gel electrophoresis ….
A. 15N is needed to weigh down the DNA samples
B. DNA molecules move towards the negative pole
C. larger molecules travel faster
D. smaller DNA fragments travel faster
This is
A. tRNA
B. mRNA
C. DNA
D. a ribosome
The process of making an mRNA strand from a DNA template is called
A. Replication
B. Transcription
C. Translation
D. Protein Synthesis
Transcription takes place in the
A. cytoplasm
B. chloroplast
C. nucleus
D. mitochondria
STRUCTURE: What Nitrogenous Base does RNA contain that DNA does not?
A. Thymine
B. Uracil
C. Adenine
D. Love
A small circular piece of DNA found in bacteria are called …
A. recombinants
B. vectors
C. plasmids
D. prokaryotes
Which of the following enzymes is NOT needed in replication?
A. DNA ligase
B. RNA primase
C. DNA polymerase III
D. RNA polymerase
Translation occurs in the:
A. office
B. cytoplasm
C. nucleus
D. cell membrane
STRUCTURE: Nucleotides monomers are made up of a sugar, a phosphate, and a:
A. nitrogenous base
B. nucleic acid
C. cholesterol
D. fatty acid
Cytosine makes up 40% of the nucleotides in a sample of DNA from an organism. Approximately what percentage of the nucleotides in this sample will be thymine?
A. 10%
B. 20%
C. 40%
D. 80%
Meselsohn and Stahl’s experiment showed that…
A. DNA is the hereditary material
B. one gene leads to one protein
C. DNA replication is semiconservative
D. the nucleus contains DNA
Which piece of genetic material is double-stranded?
A. DNA
B. mRNA
C. rRNA
D. tRNA
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