Molecular Genetics Quiz
Preview:
ATTTGAGCC- Original
ATTGAGCC – Mutated
The example above is an example of a
A. Insertion- Frameshift
B. Deletion- Substitution
C. Deletion -Frameshift
D. All of the above
In gel electrophoresis ….
A. 15N is needed to weigh down the DNA samples
B. DNA molecules move towards the negative pole
C. larger molecules travel faster
D. smaller DNA fragments travel faster
Humans have 23 pairs of chromosomes, and chimps have 24 pairs of chromosomes. What is the most likely explanation for these differences in human and chimp genomes?
A. At some point in evolution, human and chimp ancestors reproduced with each other.
B. In the evolution of chimps, new adaptations resulted from additional chromosomal material.
C. The common ancestor of humans and chimps had 24 pairs of chromosomes. During human evolution, two human chromosomes fused end to end.
D. Errors in mitosis resulted in an additional pair of chromosomes in chimps.
A virus consisting of a single strand of RNA, which is reverse transcribed into complementary DNA, is referred to as a ________.
A. bacteriophage
B. retrovirus
C. prion
D. virulent phage
STRUCTURE: Nucleotides monomers are made up of a sugar, a phosphate, and a:
A. nitrogenous base
B. nucleic acid
C. cholesterol
D. fatty acid
Which of the following information or processes does gene therapy require?
A. the ability to introduce the normal allele into the patient
B. the knowledge and availability of the defective gene but not the normal allele
C. the ability to express the introduced gene at any time in the tissue site within the patient
D. the ability to introduce a defective allele into a patient
The process of using an mRNA to make a protein is called
A. Replication
B. Transcription
C. Translation
D. Cell Division
What is Cas9 and what does it do?
A. a protein enzyme that cuts both strands of DNA at sites specified by an RNA guide
B. a DNA sequence that binds the Cas9 protein
C. an RNA molecule that binds to target DNA via complementary base pairing
D. a viral protein that disrupts bacterial membranes
STRUCTURE: Which 2 molecules form the sides of the DNA ladder?
A. deoxyribose and adenine
B. deoxyribose and a hydrogen bond
C. sugar and the nucleus
D. deoxyribose (sugar) and phosphate
Meselsohn and Stahl’s experiment showed that…
A. DNA is the hereditary material
B. one gene leads to one protein
C. DNA replication is semiconservative
D. the nucleus contains DNA
The two strands in a DNA molecule are held together by …
A. hydrogen bonds
B. phosphodiester bonds
C. covalent bonds
D. ionic bonds
HISTORY: Performed an experiment with Bacteriophage viruses that proved DNA was the genetic material
A. Maurice Wilkens and Rosalind Franklin
B. James Watson and Francis Crick
C. Alfred Hershey and Martha Chase
D. Peanut butter and Jelly
The synthesis of a new strand of DNA …
A. starts at an operator sequence.
B. involves DNA ligase.
C. is always in fragments.
D. occurs from the 5′ end to the 3′ end.
STRUCTURE: What Nitrogenous Base does RNA contain that DNA does not?
A. Thymine
B. Uracil
C. Adenine
D. Love
A DNA molecule made from 2 different sources is called …
A. recombinant DNA
B. nuclear DNA
C. modified DNA
D. mutant DNA
HISTORY: Discovered Bacterial Transformation
A. Fredrick Griffeth
B. Erwin Chargaff
C. Rosalind Franklin
D. Martha Chase
How many amino acids could be coded using the sequence 5’AUGCCCGUA3′
A. 1
B. 2
C. 3
D. 4
Liver cells differ from skin cells mainly because they…
A. have unique ribosomes.
B. use different genetic codes.
C. contain different genes.
D. express different genes.
Which of the following is a palindromic sequence?
A. GGCCCG
B. AATGGC
C. AACGTT
D. CCUTGG
HISTORY: Took the X-Ray crystallography photographs that revealed that DNA is a Double Helix
A. Rosalind Franklin
B. Linnus Pauling
C. Fredrick Griffeth
D. Martha Chase
A type of substitution in which no amino acids change is called
A. Missense
B. Nonsense
C. Silent
D. Deletion
Translation occurs in the:
A. office
B. cytoplasm
C. nucleus
D. cell membrane
Which sequence of DNA bases would pair with this partial strand
ATG TGA CAG
_
A. ATG TGA CAG
B. TAC ACT GTC
C. GTA AGT GAC
D. CAT TCA CTG
HISTORY: Discovered that A and T bond together and C and G bond together…
A. Watson and Crick
B. Rosalind Franklin
C. Fredrick Griffeth
D. Erwin Chargaff
For a repressible operon to be transcribed, which of the following conditions must occur?
A. A corepressor must be present.
B. RNA polymerase and the active repressor must be present.
C. RNA polymerase must bind to the promoter, and the repressor must be inactive.
D. RNA polymerase must not occupy the promoter, and the repressor must be inactive
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