Medical Quiz

Molecular Genetics Quiz


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Transcription takes place in the 

A. cytoplasm

B. chloroplast

C. nucleus

D. mitochondria


Which of the following is a palindromic sequence?

A. GGCCCG

B. AATGGC

C. AACGTT

D. CCUTGG


What mutation has occurred here?
T-G-A-C-C-A
T-G-A-G-C-A

A. Substitution

B. Deletion

C. Insertion

D. Frameshift


HISTORY: Discovered that A and T bond together and C and G bond together…

A. Watson and Crick

B. Rosalind Franklin

C. Fredrick Griffeth

D. Erwin Chargaff


Translation occurs in the:

A. office

B. cytoplasm

C. nucleus

D. cell membrane


In gel electrophoresis ….

A.  15N is needed to weigh down the DNA samples

B. DNA molecules move towards the negative pole

C. larger molecules travel faster

D. smaller DNA fragments travel faster


STRUCTURE: Which 2 molecules form the sides of the DNA ladder?

A. deoxyribose and adenine

B. deoxyribose and a hydrogen bond

C. sugar and the nucleus

D. deoxyribose (sugar) and phosphate


HISTORY: Performed an experiment with Bacteriophage viruses that proved DNA was the genetic material

A. Maurice Wilkens and Rosalind Franklin

B. James Watson and Francis Crick

C. Alfred Hershey and Martha Chase

D. Peanut butter and Jelly


Which piece of genetic material is double-stranded?

A. DNA

B. mRNA

C. rRNA

D. tRNA


Any change in the sequence of DNA is…

A. transgenic shift

B. Single Genotype

C. Monohybrid Trait

D. Mutation


Meselsohn and Stahl’s experiment showed that…

A. DNA is the hereditary material

B. one gene leads to one protein

C. DNA replication is semiconservative

D. the nucleus contains DNA


A DNA molecule made from 2 different sources is called …

A. recombinant DNA

B. nuclear DNA

C. modified DNA

D. mutant DNA


This is

A. tRNA

B. mRNA

C. DNA

D. a ribosome


Which sequence of DNA bases would pair with this partial strand

ATG TGA CAG
_
A. ATG TGA CAG

B. TAC ACT GTC

C. GTA AGT GAC

D. CAT TCA CTG


The two strands in a DNA molecule are held together by …

A. hydrogen bonds

B. phosphodiester bonds

C. covalent bonds

D. ionic bonds


ATTTGAGCC- Original
ATTGAGCC – Mutated
The example above is an example of a

A. Insertion- Frameshift

B. Deletion- Substitution

C. Deletion -Frameshift

D. All of the above


HISTORY: Discovered Bacterial Transformation

A. Fredrick Griffeth

B. Erwin Chargaff

C. Rosalind Franklin

D. Martha Chase


The process of using an mRNA to make a protein is called

A. Replication

B. Transcription

C. Translation

D. Cell Division


The synthesis of a new strand of DNA …

A. starts at an operator sequence.

B. involves DNA ligase.

C. is always in fragments.

D. occurs from the 5′ end to the 3′ end.


The replication of DNA is…

A. conservative

B. dispersive

C. semi-conservative

D. random


Since most amino acids are encoded for by more than one codon, the genetic code is said to be …

A. semi-conservative

B. a triplet code

C. universal

D. redundant


A type of substitution in which no  amino acids change is called 

A. Missense

B. Nonsense

C. Silent

D. Deletion


A mutation leading to an early ‘stop’ codon is a …

A. frameshift mutation

B. silent mutation

C. missense mutation

D. nonsense mutation


A small circular piece of DNA found in bacteria are called …

A. recombinants

B. vectors

C. plasmids

D. prokaryotes


HISTORY: Took the X-Ray crystallography photographs that revealed that DNA is a Double Helix

A. Rosalind Franklin

B. Linnus Pauling

C. Fredrick Griffeth

D. Martha Chase




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