Bone Marrow Histology Quiz
Preview:
How are red blood cells removed from blood?
A. Turnover
B. Macrophages
C. Migration to the gut and respiratory tract
D. Have long lifespan so just move between tissue and blood
How long can tissue macrophages live?
A. Months to years
B. 8-10 hours
C. Weeks to months
D. 5-10 days
At maturity, the majority of hematopoiesis occurs in the ____________.
A. Bone marrow
B. Liver
C. Spleen
D. Lymph nodes
Which term describes a cell that gives rise to a single, differentiated cell product?
A. Progenitor
B. Stem cell
C. Colony-forming unit
D. Differentiated
True/False: Granulocytes have a shorter lifespan than erythrocytes.
A. TRUE
B. FALSE
Hematopoiesis means:
A. Making new blood cells
B. Consuming blood cells
C. Making new reticular cells
D. Consuming reticular cells
At a later stage in granulopoiesis, does the cytoplasmic to nuclear volume ratio increase or decrease?
A. Increase
B. Decrease
True/False: Stem, progenitor, and colony-forming units are morphologically distinguishable on H&E.
A. TRUE
B. FALSE
True/False: ALL blood cells are derived from hematopoietic stem cells.
A. TRUE
B. FALSE
What is a colony stimulating factor that responds to low oxygen and stimulates red blood cell generation?
A. Granulopoietin
B. Interleukin-2
C. Interleukin-1
D. Erythropoietin
What term refers to the removal of cells from circulation?
A. Confiscation
B. Elimination
C. Withdrawal
D. Clearance
True/False: It can be normal to find plasma cells in bone marrow.
A. FALSE
B. TRUE
Macrophages are formed from __________.
A. Plasma cells
B. T lymphocytes
C. B lymphocytes
D. Monocytes
True/False: Granulocytes take a shorter time to develop than erythrocytes.
A. TRUE
B. FALSE
Where do we find precursors for B and T lymphocytes, respectively?
A. Bone marrow; bone marrow
B. Bone marrow; thymus
C. Thymus; thymus
D. Thymus; bone marrow
Platelets originate from _____________.
A. Reticulocytes
B. Macrophages
C. Megakaryocytes
D. Osteoclasts
True/False: Lymphocytes live longer in tissues than in circulation.
A. TRUE
B. FALSE
What is the first identifiable cell in the erythroid series called? Is it a large or small cell?
A. Proerythroblast; small cell
B. Proerythroblast; large cell
C. Proerythrocyte; large cell
D. Proerythrocyte; small cell
How long can B lymphocytes live?
A. One year
B. 8-10 hours
C. Weeks to months
D. 5-10 days
Bone marrow transitions from ______ to _______ as the animal matures.
A. Yellow to yellow
B. Red to yellow
C. Yellow to red
D. Red to red
True/False: Osteoclasts are fusions of monocytes.
A. TRUE
B. FALSE
Erythropoiesis refers to ____________ formation.
A. Platelet
B. Lymphocyte
C. White blood cell
D. Red blood cell
Lymphopoiesis refers to ___________ formation.
A. Platelet
B. Lymphocyte
C. Monocyte
D. Erythrocyte
True/False: Granulopoiesis is stimulated by colony stimulating factors which are only produced during an inflammatory response to an antigen.
A. TRUE
B. FALSE
Are reticulocytes a biconcave shape?
A. Yes
B. No
C. Maybe
D. Yeah… like I know
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