Bacterial Protein Synthesis Inhbitors Quiz
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A 77-year-old woman was started on antibiotics for pneumonia treatment. After 3 days of antibiotic therapy, the serum creatinine doubled. Which of the following antibiotics is most likely responsible for this increase in serum creatinine?
A. Doxycycline
B. Linezolid
C. Tobramycin
D. Clarithromycin
A routine screening nasal swab done in asymptomatic health care workers in a hospital ICU has turned up positive for MRSA in two of them. Which of the following drugs can be used topically to eradicate the organism?
A. Vancomycin
B. Linezolid
C. Fidoxamicin
D. Mupirocin
Which of the following antibiotics is an appropriate choice for the treatment of anaerobic infections?
A. Azithromycin
B. Amikacin
C. Clindamycin
D. Ciprofloxacin
Which of the following antibiotic agents should not be given to children less than 8 years of age due to its deposition in bone and teeth?
A. Azithromycin
B. Quinupristin/dalfopristin
C. Doxycycline
D. Linezolid
Which of the following statements accurately describes the difference in spectrum of activity between erythromycin and azithromycin?
A. Azithromycin has better activity against respiratory pathogens such as Haemophilus influenzae and Moraxella catarrhalis but less potent activity against staphylococci and streptococci.
B. Erythromycin has the same activity as azithromycin against gram-positives and gram-negatives
C. Azithromycin has better activity against staphylococci and streptococci compared to erythromycin
D. Erythromycin has better activity against gram-negatives such as H. influenza.
Linezolid would be a good choice for antibiotic treatment in which of the following patient scenarios?
A. Bacteremia caused by Staphylococcus aureus
B. Urinary tract infection caused by Escherichia coli
C. Pneumonia caused by drug-resistant Streptococcus pneumoniae
D. Diabetic foot infection caused by Pseudomonas aeruginosa
All bacterial protein synthesis inhibitors are bacteriostatic except
A. Tetracylines
B. Aminoglycosides
C. Linezolid
D. Azithromycin
Which of the following adverse effects is often employed as a therapeutic use for erythromycin?
A. QTc prolongation
B. Increased gastrointestinal motility
C. Photosensitivity
D. Deposition in bone
Aminoglycosides are commonly used for their concentration-dependent bactericidal activity against which group of organisms?
A. Gram-positive aerobes
B. Gram-negative aerobes
C. Gram-positive anaerobes
D. Gram-negative anaerobes
The most appropriate treatment for atypical pneumonia caused by Mycoplasma penumoniae is
A. Penicillin G
B. Amikacin
C. Linezolid
D. Azithromycin
After 5 days of clindamycin treatment for a skin infection, a patient develops diarrhea (10 watery stools/day), severe abdominal pain, and fever.
Which of the following drugs could not be given as treatment for this patient?
A. Vancomycin
B. Fidoxamicin
C. Ceftriaxone
D. Metronidazole
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